Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
Background: Staphylococcus aureus is a human pathogen that causes a wide variety of lifethreatening infections using a large number of virulence factors. One of the major global r...
—Protein binding sites are often represented by means of graphs capturing their most important geometrical and physicochemical properties. Searching for structural similarities a...
Imen Boukhris, Zied Elouedi, Thomas Fober, Marco M...
A novel approach for similarity search on the protein structure databases is proposed. PADS (Protein Alignment by Directional shape Signatures) incorporates the three dimensional ...
S. Alireza Aghili, Divyakant Agrawal, Amr El Abbad...
Background: Many structural properties such as solvent accessibility, dihedral angles and helix-helix contacts can be assigned to each residue in a membrane protein. Independent s...