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BMCBI
2007
101views more  BMCBI 2007»
13 years 9 months ago
Relationship between insertion/deletion (indel) frequency of proteins and essentiality
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
Simon K. Chan, Michael Hsing, Fereydoun Hormozdiar...
BMCBI
2008
175views more  BMCBI 2008»
13 years 9 months ago
Synonym set extraction from the biomedical literature by lexical pattern discovery
Background: Although there are a large number of thesauri for the biomedical domain many of them lack coverage in terms and their variant forms. Automatic thesaurus construction b...
John McCrae, Nigel Collier
BMCBI
2008
118views more  BMCBI 2008»
13 years 9 months ago
Kismeth: Analyzer of plant methylation states through bisulfite sequencing
Background: There is great interest in probing the temporal and spatial patterns of cytosine methylation states in genomes of a variety of organisms. It is hoped that this will sh...
Eyal Gruntman, Yijun Qi, R. Keith Slotkin, Ted Roe...
BMCBI
2007
181views more  BMCBI 2007»
13 years 9 months ago
Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D
Background: Macromolecular visualization as well as automated structural and functional annotation tools play an increasingly important role in the post-genomic era, contributing ...
Aleksey A. Porollo, Jaroslaw Meller
BMCBI
2007
109views more  BMCBI 2007»
13 years 9 months ago
Computational RNA secondary structure design: empirical complexity and improved methods
Background: We investigate the empirical complexity of the RNA secondary structure design problem, that is, the scaling of the typical difficulty of the design task for various cl...
Rosalía Aguirre-Hernández, Holger H....