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» The Distribution of Genomic Distance between Random Genomes
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IJAR
2006
125views more  IJAR 2006»
13 years 7 months ago
Computing best-possible bounds for the distribution of a sum of several variables is NP-hard
In many real-life situations, we know the probability distribution of two random variables x1 and x2, but we have no information about the correlation between x1 and x2; what are ...
Vladik Kreinovich, Scott Ferson
BMCBI
2010
113views more  BMCBI 2010»
13 years 7 months ago
Statistical method on nonrandom clustering with application to somatic mutations in cancer
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
Jingjing Ye, Adam Pavlícek, Elizabeth A. Lu...
BMCBI
2008
96views more  BMCBI 2008»
13 years 7 months ago
A PATO-compliant zebrafish screening database (MODB): management of morpholino knockdown screen information
Background: The zebrafish is a powerful model vertebrate amenable to high throughput in vivo genetic analyses. Examples include reverse genetic screens using morpholino knockdown,...
Michelle N. Knowlton, Tongbin Li, Yongliang Ren, B...
BMCBI
2007
219views more  BMCBI 2007»
13 years 7 months ago
MetaQTL: a package of new computational methods for the meta-analysis of QTL mapping experiments
Background: Integration of multiple results from Quantitative Trait Loci (QTL) studies is a key point to understand the genetic determinism of complex traits. Up to now many effor...
Jean-Baptiste Veyrieras, Bruno Goffinet, Alain Cha...
BMCBI
2006
166views more  BMCBI 2006»
13 years 7 months ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto