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BMCBI
2010
13 years 10 months ago
2010
Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...
BMCBI
2007
13 years 10 months ago
2007
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
BMCBI
2010
13 years 10 months ago
2010
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
BMCBI
2007
13 years 10 months ago
2007
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
BMCBI
2008
13 years 10 months ago
2008
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...