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BMCBI
2006
135views more  BMCBI 2006»
13 years 8 months ago
TF Target Mapper: A BLAST search tool for the identification of Transcription Factor target genes
Background: In the current era of high throughput genomics a major challenge is the genome-wide identification of target genes for specific transcription factors. Chromatin immuno...
Sebastiaan Horsman, Michael J. Moorhouse, Victor C...
BMCBI
2008
120views more  BMCBI 2008»
13 years 8 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
BMCBI
2006
203views more  BMCBI 2006»
13 years 8 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...
BMCBI
2007
99views more  BMCBI 2007»
13 years 8 months ago
Towards validating the hypothesis of phylogenetic profiling
Background: As the number of fully sequenced genome increases, the need is greater for bioinformatics to predict or annotate genes of a newly sequenced genome. Ever since Eisenber...
Raja Loganantharaj, Mazen Atwi
BIBE
2004
IEEE
128views Bioinformatics» more  BIBE 2004»
14 years 13 days ago
Towards a Proteomics Meta-Classification
There is a recognized need for a meta-classification that can serve as a foundation for more refined ontologies in the field of proteomics. Standard data sources classify proteins...
Anand Kumar, Barry Smith