In this paper we model and simulate a biological system describing the evolution of cancer stem cells into tumors. Starting from some basic hypotheses about the behavior of these ...
Evolution is a permanent challenge in product line engineering. Reusable assets such as software components or documents evolve continuously due to new customer requirements or te...
1 Even though there has been some research on system evolution, there is no well defined vocabulary to indicate deviation of a system from desired goals. Further, there are no obje...
This paper summarizes an approach to support evolution of software models by means of a transformation catalogue. These transformations treat UML class diagram models, OCL constrai...
We introduce a Markov model for the evolution of a gene family along a phylogeny. The model includes parameters for the rates of horizontal gene transfer, gene duplication, and gen...