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BMCBI
2010
134views more  BMCBI 2010»
13 years 7 months ago
BayesMotif: de novo protein sorting motif discovery from impure datasets
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Jianjun Hu, Fan Zhang
BIBM
2009
IEEE
156views Bioinformatics» more  BIBM 2009»
14 years 16 days ago
Bayesian Classifier for Anchored Protein Sorting Discovery
—A typical cell has a size of only 10 µm while it contains about a billion proteins. Transportation of these proteins from their synthesis sites to their target locations within...
Fan Zhang, Jianjun Hu
BMCBI
2007
133views more  BMCBI 2007»
13 years 7 months ago
MATLIGN: a motif clustering, comparison and matching tool
Background: Sequence motifs representing transcription factor binding sites (TFBS) are commonly encoded as position frequency matrices (PFM) or degenerate consensus sequences (CS)...
Matti Kankainen, Ari Löytynoja
BMCBI
2010
124views more  BMCBI 2010»
13 years 7 months ago
The value of position-specific priors in motif discovery using MEME
Background: Position-specific priors have been shown to be a flexible and elegant way to extend the power of Gibbs sampler-based motif discovery algorithms. Information of many ty...
Timothy L. Bailey, Mikael Bodén, Tom Whitin...
RECOMB
2007
Springer
14 years 7 months ago
Network Motif Discovery Using Subgraph Enumeration and Symmetry-Breaking
The study of biological networks and network motifs can yield significant new insights into systems biology. Previous methods of discovering network motifs ? network-centric subgra...
Joshua A. Grochow, Manolis Kellis