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» The Pfam protein families database
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BMCBI
2007
99views more  BMCBI 2007»
13 years 7 months ago
RepSeq - A database of amino acid repeats present in lower eukaryotic pathogens
Background: Amino acid repeat-containing proteins have a broad range of functions and their identification is of relevance to many experimental biologists. In human-infective prot...
Daniel P. Depledge, Ryan P. J. Lower, Deborah F. S...
NAR
2002
164views more  NAR 2002»
13 years 7 months ago
SCOP database in 2002: refinements accommodate structural genomics
The SCOP (Structural Classification of Proteins) database is a comprehensive ordering of all proteins of known structure, according to their evolutionary and structural relationsh...
Loredana Lo Conte, Steven E. Brenner, Tim J. P. Hu...
BMCBI
2004
83views more  BMCBI 2004»
13 years 7 months ago
VKCDB: Voltage-gated potassium channel database
Background: The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based com...
Bin Li, Warren J. Gallin
BMCBI
2004
96views more  BMCBI 2004»
13 years 7 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2004
125views more  BMCBI 2004»
13 years 7 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...