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» The Power of Comparative Reasoning
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130
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BMCBI
2007
171views more  BMCBI 2007»
15 years 3 months ago
An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed,
Background: Identifying relevant research in an ever-growing body of published literature is becoming increasingly difficult. Establishing domain-specific knowledge bases may be a...
Wei Yu, Ajay Yesupriya, Anja Wulf, Junfeng Qu, Mui...
112
Voted
BMCBI
2007
94views more  BMCBI 2007»
15 years 3 months ago
False positive reduction in protein-protein interaction predictions using gene ontology annotations
Background: Many crucial cellular operations such as metabolism, signalling, and regulations are based on protein-protein interactions. However, the lack of robust protein-protein...
Mahmood A. Mahdavi, Yen-Han Lin
126
Voted
BMCBI
2008
95views more  BMCBI 2008»
15 years 3 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
135
Voted
BMCBI
2008
120views more  BMCBI 2008»
15 years 3 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
131
Voted
BMCBI
2008
110views more  BMCBI 2008»
15 years 3 months ago
Testing for treatment effects on gene ontology
In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functi...
Taewon Lee, Varsha G. Desai, Cruz Velasco, Robert ...