A stochastic genetic toggle switch model that consists of two identical, mutually repressive genes is built using the Gillespie algorithm with time delays as an example of a simpl...
Gene regulatory network model is the most widely used mechanism to model and predict the behavior of living organisms. Network Component Analysis (NCA) as an emerging issue for unc...
When we try to implement a multi-objective genetic algorithm (MOGA) with variable weights for finding a set of Pareto optimal solutions, one difficulty lies in determining appropri...
In gene expression data a bicluster is a subset of genes and a subset of conditions which show correlating levels of expression. However, the problem of finding significant biclu...
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...