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BMCBI
2007
91views more  BMCBI 2007»
13 years 11 months ago
A mass accuracy sensitive probability based scoring algorithm for database searching of tandem mass spectrometry data
Background: Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) has become one of the most used tools in mass spectrometry based proteomics. Various algorithms ...
Hua Xu, Michael A. Freitas
BMCBI
2008
102views more  BMCBI 2008»
13 years 11 months ago
Significance analysis of microarray for relative quantitation of LC/MS data in proteomics
Background: Although fold change is a commonly used criterion in quantitative proteomics for differentiating regulated proteins, it does not provide an estimation of false positiv...
Bryan A. P. Roxas, Qingbo Li
BMCBI
2006
116views more  BMCBI 2006»
13 years 11 months ago
TaxMan: a taxonomic database manager
Background: Phylogenetic analysis of large, multiple-gene datasets, assembled from public sequence databases, is rapidly becoming a popular way to approach difficult phylogenetic ...
Martin Jones, Mark Blaxter
DILS
2007
Springer
14 years 1 months ago
A High-Throughput Bioinformatics Platform for Mass Spectrometry-Based Proteomics
The success of mass spectrometry-based proteomics in emerging applications such as biomarker discovery and clinical diagnostics, is predicated substantially on its ability to achie...
Thodoros Topaloglou, Moyez Dharsee, Rob M. Ewing, ...
BMCBI
2008
153views more  BMCBI 2008»
13 years 11 months ago
2DB: a Proteomics database for storage, analysis, presentation, and retrieval of information from mass spectrometric experiments
Background: The amount of information stemming from proteomics experiments involving (multi dimensional) separation techniques, mass spectrometric analysis, and computational anal...
Jens Allmer, Sebastian Kuhlgert, Michael Hippler