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BMCBI
2007
102views more  BMCBI 2007»
13 years 6 months ago
Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
Mark C. Emerick, Giovanni Parmigiani, William S. A...
ALMOB
2006
109views more  ALMOB 2006»
13 years 6 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
CORR
2010
Springer
179views Education» more  CORR 2010»
13 years 4 months ago
The DMM bound: multivariate (aggregate) separation bounds
In this paper we derive aggregate separation bounds, named after Davenport-MahlerMignotte (DMM), on the isolated roots of polynomial systems, specifically on the minimum distance ...
Ioannis Z. Emiris, Bernard Mourrain, Elias P. Tsig...
JMLR
2011
148views more  JMLR 2011»
13 years 1 months ago
Multitask Sparsity via Maximum Entropy Discrimination
A multitask learning framework is developed for discriminative classification and regression where multiple large-margin linear classifiers are estimated for different predictio...
Tony Jebara
BMCBI
2008
138views more  BMCBI 2008»
13 years 6 months ago
Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
Yin-Jing Tien, Yun-Shien Lee, Han-Ming Wu, Chun-Ho...