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BMCBI
2006
124views more  BMCBI 2006»
13 years 8 months ago
The development and validation of the Virtual Tissue Matrix, a software application that facilitates the review of tissue microa
Background: The Tissue Microarray (TMA) facilitates high-throughput analysis of hundreds of tissue specimens simultaneously. However, bottlenecks in the storage and manipulation o...
Catherine M. Conway, Deirdre O'Shea, Sallyann O'Br...
BMCBI
2006
97views more  BMCBI 2006»
13 years 8 months ago
Selecting normalization genes for small diagnostic microarrays
Background: Normalization of gene expression microarrays carrying thousands of genes is based on assumptions that do not hold for diagnostic microarrays carrying only few genes. T...
Jochen Jaeger, Rainer Spang
BMCBI
2006
112views more  BMCBI 2006»
13 years 8 months ago
Protein disorder prediction by condensed PSSM considering propensity for order or disorder
Background: More and more disordered regions have been discovered in protein sequences, and many of them are found to be functionally significant. Previous studies reveal that dis...
Chung-Tsai Su, Chien-Yu Chen, Yu-Yen Ou
BMCBI
2006
157views more  BMCBI 2006»
13 years 8 months ago
Comparison of protein interaction networks reveals species conservation and divergence
Background: Recent progresses in high-throughput proteomics have provided us with a first chance to characterize protein interaction networks (PINs), but also raised new challenge...
Zhi Liang, Meng Xu, Maikun Teng, Liwen Niu
BMCBI
2006
127views more  BMCBI 2006»
13 years 8 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...
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