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BMCBI
2008
120views more  BMCBI 2008»
15 years 6 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
BMCBI
2007
148views more  BMCBI 2007»
15 years 6 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
BMCBI
2007
167views more  BMCBI 2007»
15 years 6 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk
ICDE
2004
IEEE
133views Database» more  ICDE 2004»
16 years 7 months ago
GenExplore: Interactive Exploration of Gene Interactions from Microarray Data
DNA Microarray provides a powerful basis for analysis of gene expression. Data mining methods such as clustering have been widely applied to microarray data to link genes that sho...
Yong Ye, Xintao Wu, Kalpathi R. Subramanian, Liyin...
RECOMB
2001
Springer
16 years 6 months ago
Class discovery in gene expression data
Recent studies (Alizadeh et al, [1]; Bittner et al,[5]; Golub et al, [11]) demonstrate the discovery of putative disease subtypes from gene expression data. The underlying computa...
Amir Ben-Dor, Nir Friedman, Zohar Yakhini