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BMCBI
2005
198views more  BMCBI 2005»
15 years 5 months ago
Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
BMCBI
2002
76views more  BMCBI 2002»
15 years 5 months ago
The SGS3 protein involved in PTGS finds a family
Background: Post transcriptional gene silencing (PTGS) is a recently discovered phenomenon that is an area of intense research interest. Components of the PTGS machinery are being...
Alex Bateman
BIBM
2010
IEEE
144views Bioinformatics» more  BIBM 2010»
15 years 4 months ago
Identification and quantification of abundant species from pyrosequences of 16S rRNA by consensus alignment
16S rRNA gene profiling has recently been boosted by the development of pyrosequencing methods. A common analysis is to group pyrosequences into Operational Taxonomic Units (OTUs),...
Yuzhen Ye
BMCBI
2010
126views more  BMCBI 2010»
15 years 3 months ago
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Gürkan Bebek, Vishal Patel, Mark R. Chance
BMCBI
2007
145views more  BMCBI 2007»
15 years 6 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...