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RECOMB
2004
Springer
14 years 7 months ago
Somatic evolution of cancer
We study a situation that arises in the somatic evolution of cancer. Consider a finite population of replicating cells and a sequence of mutations: type 0 can mutate to type 1, wh...
Martin Nowak
PROCEDIA
2010
120views more  PROCEDIA 2010»
13 years 2 months ago
A coupled convection-diffusion level set model for tracking epithelial cells in colonic crypts
Colorectal cancer is initiated in colonic crypts as a consequence of alterations leading to the disruption of the normal colonic cellular process. We propose a model, which couple...
Isabel N. Figueiredo, Carlos F. Leal, Tommaso Leon...
EVOW
2006
Springer
13 years 11 months ago
Hierarchical Clustering, Languages and Cancer
In this paper, we introduce a novel objective function for the hierarchical clustering of data from distance matrices, a very relevant task in Bioinformatics. To test the robustnes...
Pritha Mahata, Wagner Costa, Carlos Cotta, Pablo M...
BMCBI
2008
164views more  BMCBI 2008»
13 years 7 months ago
MeInfoText: associated gene methylation and cancer information from text mining
Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
Yu-Ching Fang, Hsuan-Cheng Huang, Hsueh-Fen Juan
ISCIS
2004
Springer
14 years 25 days ago
Biological Metaphors for Agent Behavior
A wide variety of practical problems related to the interaction of agents can be examined using biological metaphors. This paper applies the theory of G-networks to agent systems b...
Erol Gelenbe, Varol Kaptan, Yu Wang