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BMCBI
2008
95views more  BMCBI 2008»
13 years 8 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2008
102views more  BMCBI 2008»
13 years 8 months ago
Stability of the core domain of p53: insights from computer simulations
: The tumour suppressor protein p53 protein has a core domain that binds DNA and is the site for most oncogenic mutations. This domain is quite unstable compared to its homologs p...
Arumugam Madhumalar, Derek John Smith, Chandra Ver...
EC
2006
121views ECommerce» more  EC 2006»
13 years 7 months ago
A Study of Structural and Parametric Learning in XCS
The performance of a learning classifier system is due to its two main components. First, it evolves new structures by generating new rules in a genetic process; second, it adjust...
Tim Kovacs, Manfred Kerber
BMCBI
2007
165views more  BMCBI 2007»
13 years 7 months ago
Automatic reconstruction of a bacterial regulatory network using Natural Language Processing
Background: Manual curation of biological databases, an expensive and labor-intensive process, is essential for high quality integrated data. In this paper we report the implement...
Carlos Rodríguez Penagos, Heladia Salgado, ...
BMCBI
2007
151views more  BMCBI 2007»
13 years 7 months ago
The Genopolis Microarray Database
Background: Gene expression databases are key resources for microarray data management and analysis and the importance of a proper annotation of their content is well understood. ...
Andrea Splendiani, Marco Brandizi, Gael Even, Otta...
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