72 search results - page 11 / 15 » The impact of sample imbalance on identifying differentially... |
BIBM
2009
IEEE
14 years 2 months ago
2009
IEEE
Background: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address...
BMCBI
2010
13 years 2 months ago
2010
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...
BMCBI
2008
13 years 8 months ago
2008
Background: Gene expression profiling has the potential to unravel molecular mechanisms behind gene regulation and identify gene targets for therapeutic interventions. As microarr...
BMCBI
2007
13 years 8 months ago
2007
Background: Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs) that are differentially utilized in different tissues and cell lines. ...
BMCBI
2006
13 years 8 months ago
2006
Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple ...