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BMCBI
2010
117views more  BMCBI 2010»
13 years 7 months ago
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
Tim Harder, Wouter Boomsma, Martin Paluszewski, Je...
BMCBI
2008
155views more  BMCBI 2008»
13 years 7 months ago
AMMOS: Automated Molecular Mechanics Optimization tool for in silico Screening
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...
Tania Pencheva, David Lagorce, Ilza Pajeva, Bruno ...
EMSOFT
2005
Springer
14 years 1 months ago
AutoDVS: an automatic, general-purpose, dynamic clock scheduling system for hand-held devices
We present AutoDVS, a dynamic voltage scaling (DVS) system for hand-held computers. Unlike extant DVS systems, AutoDVS distinguishes common, course-grain, program behavior and cou...
Selim Gurun, Chandra Krintz
BMCBI
2010
190views more  BMCBI 2010»
13 years 7 months ago
Sample size and statistical power considerations in high-dimensionality data settings: a comparative study of classification alg
Background: Data generated using `omics' technologies are characterized by high dimensionality, where the number of features measured per subject vastly exceeds the number of...
Yu Guo, Armin Graber, Robert N. McBurney, Raji Bal...
RECOMB
2006
Springer
14 years 7 months ago
New Methods for Detecting Lineage-Specific Selection
Abstract. So far, most methods for identifying sequences under selection based on comparative sequence data have either assumed selectional pressures are the same across all branch...
Adam C. Siepel, Katherine S. Pollard, David Haussl...