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BMCBI
2010
13 years 7 months ago
2010
Background: Meta-analysis methods exist for combining multiple microarray datasets. However, there are a wide range of issues associated with microarray meta-analysis and a limite...
BMCBI
2007
13 years 7 months ago
2007
Background: Modelling of time series data should not be an approximation of input data profiles, but rather be able to detect and evaluate dynamical changes in the time series dat...
BMCBI
2007
13 years 7 months ago
2007
Background: A microarray study may select different differentially expressed gene sets because of different selection criteria. For example, the fold-change and p-value are two co...
BMCBI
2008
13 years 7 months ago
2008
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
BMCBI
2008
13 years 7 months ago
2008
In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functi...