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» Theoretical and Experimental DNA Computation
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DNA
2007
Springer
159views Bioinformatics» more  DNA 2007»
14 years 27 days ago
Activatable Tiles: Compact, Robust Programmable Assembly and Other Applications
While algorithmic DNA self-assembly is, in theory, capable of forming complex patterns, its experimental demonstration has been limited by significant assembly errors. In this pa...
Urmi Majumder, Thomas H. LaBean, John H. Reif
WABI
2007
Springer
139views Bioinformatics» more  WABI 2007»
14 years 25 days ago
Computability of Models for Sequence Assembly
Graph-theoretic models have come to the forefront as some of the most powerful and practical methods for sequence assembly. Simultaneously, the computational hardness of the underl...
Paul Medvedev, Konstantinos Georgiou, Gene Myers, ...
IMSCCS
2006
IEEE
14 years 23 days ago
Degenerated Primer Design to Amplify the Heavy Chain Variable Region from Immunoglobulin cDNA
Background: The amplification of variable regions of immunoglobulins has become a major challenge in the cloning of antibody genes, whether from hybridoma cell lines or splenic B ...
Wang Ying, Chen Wei, Li Xu, Cheng Bing
RECOMB
2007
Springer
14 years 7 months ago
Design of Compact, Universal DNA Microarrays for Protein Binding Microarray Experiments
Our group has recently developed a compact, universal protein binding microarray (PBM) that can be used to determine the binding preferences of transcription factors (TFs) [1]. Thi...
Anthony A. Philippakis, Aaron M. Qureshi, Michael ...
RECOMB
2004
Springer
14 years 7 months ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler