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BMCBI
2008
92views more  BMCBI 2008»
13 years 8 months ago
OpenMS - An open-source software framework for mass spectrometry
Background: Mass spectrometry is an essential analytical technique for high-throughput analysis in proteomics and metabolomics. The development of new separation techniques, preci...
Marc Sturm, Andreas Bertsch, Clemens Gröpl, A...
BMCBI
2008
142views more  BMCBI 2008»
13 years 8 months ago
Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification
Background: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produ...
Irene Kouskoumvekaki, Zhiyong Yang, Svava Ó...
BMCBI
2007
167views more  BMCBI 2007»
13 years 8 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
BMCBI
2007
179views more  BMCBI 2007»
13 years 8 months ago
Automated smoother for the numerical decoupling of dynamics models
Background: Structure identification of dynamic models for complex biological systems is the cornerstone of their reverse engineering. Biochemical Systems Theory (BST) offers a pa...
Marco Vilela, Carlos Cristiano H. Borges, Susana V...
BMCBI
2010
151views more  BMCBI 2010»
13 years 8 months ago
Data reduction for spectral clustering to analyze high throughput flow cytometry data
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
Habil Zare, Parisa Shooshtari, Arvind Gupta, Ryan ...