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» TopoGSA: network topological gene set analysis
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BMCBI
2008
114views more  BMCBI 2008»
13 years 9 months ago
The pairwise disconnectivity index as a new metric for the topological analysis of regulatory networks
Background: Currently, there is a gap between purely theoretical studies of the topology of large bioregulatory networks and the practical traditions and interests of experimental...
Anatolij Potapov, Björn Goemann, Edgar Wingen...
ALIFE
2008
13 years 8 months ago
Exploring the Operational Characteristics of Inference Algorithms for Transcriptional Networks by Means of Synthetic Data
The development of structure-learning algorithms for gene regulatory networks depends heavily on the availability of synthetic data sets that contain both the original network and ...
Koenraad Van Leemput, Tim Van den Bulcke, Thomas D...
BMCBI
2010
153views more  BMCBI 2010»
13 years 7 months ago
DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
Bruno M. Tesson, Rainer Breitling, Ritsert C. Jans...
BMCBI
2010
97views more  BMCBI 2010»
13 years 3 months ago
A semi-parametric Bayesian model for unsupervised differential co-expression analysis
Background: Differential co-expression analysis is an emerging strategy for characterizing disease related dysregulation of gene expression regulatory networks. Given pre-defined ...
Johannes M. Freudenberg, Siva Sivaganesan, Michael...
BMCBI
2004
207views more  BMCBI 2004»
13 years 8 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...