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AMAI
2008
Springer
15 years 2 months ago
The giving tree: constructing trees for efficient offline and online multi-robot coverage
This paper discusses the problem of building efficient coverage paths for a team of robots. An efficient multi-robot coverage algorithm should result in a coverage path for every ...
Noa Agmon, Noam Hazon, Gal A. Kaminka
BMCBI
2010
156views more  BMCBI 2010»
15 years 2 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
BMCBI
2010
116views more  BMCBI 2010»
15 years 2 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
BMCBI
2010
109views more  BMCBI 2010»
15 years 2 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2007
104views more  BMCBI 2007»
15 years 2 months ago
TISs-ST: a web server to evaluate polymorphic translation initiation sites and their reflections on the secretory targets
Background: The nucleotide sequence flanking the translation initiation codon (start codon context) affects the translational efficiency of eukaryotic mRNAs, and may indicate the ...
Renato Vicentini, Marcelo Menossi