Here we investigate an extension of a previously suggested "automatic amide I frequency selection procedure" where we introduce an additional criterion utilizing empiric...
Joachim A. Hering, Peter R. Innocent, Parvez I. Ha...
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
One of the aims of modern Bioinformatics is to discover the molecular mechanisms that rule the protein operation. This would allow us to understand the complex processes involved i...
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski...