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» Transcriptional regulation at a glance
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NAR
2011
204views Computer Vision» more  NAR 2011»
12 years 10 months ago
CLIPZ: a database and analysis environment for experimentally determined binding sites of RNA-binding proteins
The stability, localization and translation rate of mRNAs are regulated by a multitude of RNAbinding proteins (RBPs) that find their targets directly or with the help of guide RNA...
Mohsen Khorshid, Christoph Rodak, Mihaela Zavolan
RECOMB
2003
Springer
14 years 8 months ago
Physical network models and multi-source data integration
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
Chen-Hsiang Yeang, Tommi Jaakkola
WABI
2009
Springer
124views Bioinformatics» more  WABI 2009»
14 years 2 months ago
Mimosa: Mixture Model of Co-expression to Detect Modulators of Regulatory Interaction
Background: Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often use...
Matthew Hansen, Logan Everett, Larry Singh, Sridha...
IMSCCS
2006
IEEE
14 years 1 months ago
Frequency Distribution of TATA Box and Extension Sequences on Human Promoters
Background: TATA box is one of the most important transcription factor binding sites. But the exact sequences of TATA box are still not very clear. Results: In this study, we cond...
Wei Shi, Wanlei Zhou
BMCBI
2010
95views more  BMCBI 2010»
13 years 7 months ago
An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...