Background: New technologies are enabling the measurement of many types of genomic and epigenomic information at scales ranging from the atomic to nuclear. Much of this new data i...
Thomas M. Asbury, Matt Mitman, Jijun Tang, W. Jim ...
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
Background: The development and testing of functions for the modeling of protein energetics is an important part of current research aimed at understanding protein structure and f...
Background: Normal mode analysis (NMA) has become the method of choice to investigate the slowest motions in macromolecular systems. NMA is especially useful for large biomolecula...
Background: Pattern matching is the core of bioinformatics; it is used in database searching, restriction enzyme mapping, and finding open reading frames. It is done repeatedly ov...