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BMCBI
2006
114views more  BMCBI 2006»
13 years 11 months ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen
BMCBI
2006
133views more  BMCBI 2006»
13 years 11 months ago
An integrated approach to the prediction of domain-domain interactions
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen
BMCBI
2007
182views more  BMCBI 2007»
13 years 11 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
NAR
2008
141views more  NAR 2008»
13 years 11 months ago
MethyCancer: the database of human DNA methylation and cancer
Cancer is ranked as one of the top killers in all human diseases and continues to have a devastating effect on the population around the globe. Current research efforts are aiming...
Ximiao He, Suhua Chang, Jiajie Zhang, Qian Zhao, H...
IIE
2007
120views more  IIE 2007»
13 years 11 months ago
Words are Silver, Mouse-Clicks are Gold? (or how to optimize the level of language formalization of young students in a Logo-bas
How do we teach children to express and communicate ideas in a formal and informal mode? What type of language do they need in a concrete context? How should they determine a prope...
Evgenia Sendova, Toni Chehlarova, Pavel Boytchev