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» Unfolding of Microarray Data
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BMCBI
2007
144views more  BMCBI 2007»
13 years 8 months ago
Accelerated search for biomolecular network models to interpret high-throughput experimental data
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
Suman Datta, Bahrad A. Sokhansanj
KDD
2003
ACM
142views Data Mining» more  KDD 2003»
14 years 8 months ago
Mining phenotypes and informative genes from gene expression data
Mining microarray gene expression data is an important research topic in bioinformatics with broad applications. While most of the previous studies focus on clustering either gene...
Chun Tang, Aidong Zhang, Jian Pei
BMCBI
2010
115views more  BMCBI 2010»
13 years 8 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2006
130views more  BMCBI 2006»
13 years 8 months ago
Spatial normalization of array-CGH data
Background: Array-based comparative genomic hybridization (array-CGH) is a recently developed technique for analyzing changes in DNA copy number. As in all microarray analyses, no...
Pierre Neuvial, Philippe Hupé, Isabel Brito...
BMCBI
2007
182views more  BMCBI 2007»
13 years 8 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen