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» Using Meta-Structures in Database Design
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BMCBI
2006
124views more  BMCBI 2006»
13 years 7 months ago
The development and validation of the Virtual Tissue Matrix, a software application that facilitates the review of tissue microa
Background: The Tissue Microarray (TMA) facilitates high-throughput analysis of hundreds of tissue specimens simultaneously. However, bottlenecks in the storage and manipulation o...
Catherine M. Conway, Deirdre O'Shea, Sallyann O'Br...
BMCBI
2006
128views more  BMCBI 2006»
13 years 7 months ago
Model-driven user interfaces for bioinformatics data resources: regenerating the wheel as an alternative to reinventing it
Background: The proliferation of data repositories in bioinformatics has resulted in the development of numerous interfaces that allow scientists to browse, search and analyse the...
Kevin L. Garwood, Christopher Garwood, Cornelia He...
BMCBI
2007
116views more  BMCBI 2007»
13 years 7 months ago
Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases
Background: The pyridine nucleotide disulfide reductase (PNDR) is a large and heterogeneous protein family divided into two classes (I and II), which reflect the divergent evoluti...
César L. Avila, Viviana A. Rapisarda, Ricar...
CN
2007
133views more  CN 2007»
13 years 7 months ago
Automatic high-performance reconstruction and recovery
Self-protecting systems require the ability to instantaneously detect malicious activity at run-time and prevent execution. We argue that it is impossible to perfectly self-protec...
Ashvin Goel, Wu-chang Feng, Wu-chi Feng, David Mai...
BMCBI
2005
123views more  BMCBI 2005»
13 years 7 months ago
PSI-BLAST-ISS: an intermediate sequence search tool for estimation of the position-specific alignment reliability
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
Mindaugas Margelevicius, Ceslovas Venclovas