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» Using PQ Trees for Comparative Genomics
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BIRD
2008
Springer
177views Bioinformatics» more  BIRD 2008»
13 years 9 months ago
Fast Structured Motif Search in DNA Sequences
We study the problem of structured motif search in DNA sequences. This is a fundamental task in bioinformatics which contributes to better understanding of genome characteristics a...
Mihail Halachev, Nematollaah Shiri
ISMB
2007
13 years 10 months ago
Computational prediction of host-pathogen protein-protein interactions
Our major effort in this reporting period comprised functional genomic studies of key genes for carbon metabolite and nodulation/nitrogen fixation in Sinorhizobium meliloti, compar...
Matthew D. Dyer, T. M. Murali, Bruno W. S. Sobral
RECOMB
2006
Springer
14 years 8 months ago
Identifiability Issues in Phylogeny-Based Detection of Horizontal Gene Transfer
Prokaryotic organisms share genetic material across species boundaries by means of a process known as horizontal gene transfer (HGT). Detecting this process bears great significanc...
Cuong Than, Derek A. Ruths, Hideki Innan, Luay Nak...
BMCBI
2007
131views more  BMCBI 2007»
13 years 7 months ago
An improved method for identifying functionally linked proteins using phylogenetic profiles
Background: Phylogenetic profiles record the occurrence of homologs of genes across fully sequenced organisms. Proteins with similar profiles are typically components of protein c...
Shawn Cokus, Sayaka Mizutani, Matteo Pellegrini
BMCBI
2010
155views more  BMCBI 2010»
13 years 5 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...