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BMCBI
2004
101views more  BMCBI 2004»
13 years 8 months ago
A database for G proteins and their interaction with GPCRs
Background: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their interaction with G proteins, which act as switches forming ...
Antigoni L. Elefsinioti, Pantelis G. Bagos, Ioanni...
BMCBI
2007
112views more  BMCBI 2007»
13 years 9 months ago
PFAAT version 2.0: A tool for editing, annotating, and analyzing multiple sequence alignments
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...
HPDC
2010
IEEE
13 years 9 months ago
Modeling sequence and function similarity between proteins for protein functional annotation
A common task in biological research is to predict function for proteins by comparing sequences between proteins of known and unknown function. This is often done using pair-wise ...
Roger Higdon, Brenton Louie, Eugene Kolker
BMCBI
2005
152views more  BMCBI 2005»
13 years 8 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
DATESO
2010
169views Database» more  DATESO 2010»
13 years 6 months ago
Parametrised Hausdorff Distance as a Non-Metric Similarity Model for Tandem Mass Spectrometry
Abstract. Tandem mass spectrometry is a widely used method for protein and peptide sequences identification. Since the mass spectra contain up to 80% of noise and many other inaccu...
Jiri Novák, David Hoksza