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BMCBI
2004
101views more  BMCBI 2004»
13 years 7 months ago
A database for G proteins and their interaction with GPCRs
Background: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their interaction with G proteins, which act as switches forming ...
Antigoni L. Elefsinioti, Pantelis G. Bagos, Ioanni...
BMCBI
2011
12 years 11 months ago
ENGINES: exploring single nucleotide variation in entire human genomes
Background: Next generation ultra-sequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences, and therefore new softw...
Jorge Amigo, Antonio Salas, Christopher Phillips
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
TOPSAN: a collaborative annotation environment for structural genomics
Background: Many protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositi...
Dana Weekes, S. Sri Krishna, Constantina Bakolitsa...
WIKIS
2006
ACM
14 years 1 months ago
Semantic Wikipedia
Wikipedia is the world’s largest collaboratively edited source of encyclopaedic knowledge. But in spite of its utility, its contents are barely machine-interpretable. Structural...
Heiko Haller, Markus Krötzsch, Max Völke...
NAR
2011
248views Computer Vision» more  NAR 2011»
12 years 10 months ago
NCBI GEO: archive for functional genomics data sets - 10 years on
A decade ago, the Gene Expression Omnibus (GEO) database was established at the National Center for Biotechnology Information (NCBI). The original objective of GEO was to serve as...
Tanya Barrett, Dennis B. Troup, Stephen E. Wilhite...