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» Using context to improve protein domain identification
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BMCBI
2005
97views more  BMCBI 2005»
13 years 9 months ago
Sequence variation in ligand binding sites in proteins
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
Thomas J. Magliery, Lynne Regan
BMCBI
2008
124views more  BMCBI 2008»
13 years 10 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
BMCBI
2010
127views more  BMCBI 2010»
13 years 10 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
BMCBI
2007
131views more  BMCBI 2007»
13 years 10 months ago
On the detection of functionally coherent groups of protein domains with an extension to protein annotation
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...
DEXAW
2009
IEEE
139views Database» more  DEXAW 2009»
14 years 4 months ago
Improving Web Page Retrieval Using Search Context from Clicked Domain Names
Abstract—Search context is a crucial factor that helps to understand a user’s information need in ad-hoc Web page retrieval. A query log of a search engine contains rich inform...
Rongmei Li