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BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 7 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
ALT
2004
Springer
13 years 11 months ago
Applications of Regularized Least Squares to Classification Problems
Abstract. We present a survey of recent results concerning the theoretical and empirical performance of algorithms for learning regularized least-squares classifiers. The behavior ...
Nicolò Cesa-Bianchi
BMCBI
2008
127views more  BMCBI 2008»
13 years 7 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
BMCBI
2007
138views more  BMCBI 2007»
13 years 7 months ago
A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic
Background: A key challenge in metabonomics is to uncover quantitative associations between multidimensional spectroscopic data and biochemical measures used for disease risk asse...
Aki Vehtari, Ville-Petteri Mäkinen, Pasi Soin...
KDD
2008
ACM
232views Data Mining» more  KDD 2008»
14 years 8 months ago
Anticipating annotations and emerging trends in biomedical literature
The BioJournalMonitor is a decision support system for the analysis of trends and topics in the biomedical literature. Its main goal is to identify potential diagnostic and therap...
Bernd Wachmann, Dmitriy Fradkin, Fabian Mörch...