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» Validating associations in biological databases
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BMCBI
2008
184views more  BMCBI 2008»
13 years 10 months ago
Integrating protein-protein interactions and text mining for protein function prediction
Background: Functional annotation of proteins remains a challenging task. Currently the scientific literature serves as the main source for yet uncurated functional annotations, b...
Samira Jaeger, Sylvain Gaudan, Ulf Leser, Dietrich...
BMCBI
2007
120views more  BMCBI 2007»
13 years 10 months ago
Transcript-based redefinition of grouped oligonucleotide probe sets using AceView: High-resolution annotation for microarrays
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...
BMCBI
2005
141views more  BMCBI 2005»
13 years 9 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
SC
2009
ACM
14 years 4 months ago
Evaluating use of data flow systems for large graph analysis
Large graph analysis has become increasingly important and is widely used in many applications such as web mining, social network analysis, biology, and information retrieval. The...
Andy Yoo, Ian Kaplan
BMCBI
2010
178views more  BMCBI 2010»
13 years 10 months ago
CNV Workshop: an integrated platform for high-throughput copy number variation discovery and clinical diagnostics
Background: Recent studies have shown that copy number variations (CNVs) are frequent in higher eukaryotes and associated with a substantial portion of inherited and acquired risk...
Xiaowu Gai, Juan C. Perin, Kevin Murphy, Ryan O'Ha...