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PVLDB
2008
163views more  PVLDB 2008»
13 years 8 months ago
C-DEM: a multi-modal query system for Drosophila Embryo databases
The amount of biological data publicly available has experienced an exponential growth as the technology advances. Online databases are now playing an important role as informatio...
Fan Guo, Lei Li, Christos Faloutsos, Eric P. Xing
BMCBI
2011
13 years 17 days ago
Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Datase
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
Chris Bauer, Frank Kleinjung, Celia J. Smith, Mark...
BMCBI
2007
97views more  BMCBI 2007»
13 years 9 months ago
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
Carmen Lai, Hugo M. Horlings, Marc J. van de Vijve...
BMCBI
2008
148views more  BMCBI 2008»
13 years 9 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan
BIOINFORMATICS
2006
92views more  BIOINFORMATICS 2006»
13 years 9 months ago
What should be expected from feature selection in small-sample settings
Motivation: High-throughput technologies for rapid measurement of vast numbers of biological variables offer the potential for highly discriminatory diagnosis and prognosis; howev...
Chao Sima, Edward R. Dougherty