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BMCBI
2006
13 years 7 months ago
2006
Background: Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement ...
BMCBI
2008
13 years 7 months ago
2008
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
BMCBI
2007
13 years 7 months ago
2007
Background: The nucleotide sequence flanking the translation initiation codon (start codon context) affects the translational efficiency of eukaryotic mRNAs, and may indicate the ...
BMCBI
2010
13 years 7 months ago
2010
Background: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing application...
WWW
2007
ACM
14 years 8 months ago
2007
ACM
Many applications in analytical domains often have the need to "connect the dots" i.e., query about the structure of data. In bioinformatics for example, it is typical t...