Background: Whole genome association studies using highly dense single nucleotide polymorphisms (SNPs) are a set of methods to identify DNA markers associated with variation in a ...
Stephen J. Goodswen, Cedric Gondro, Nathan S. Wats...
Background: With the current technological advances in high-throughput biology, the necessity to develop tools that help to analyse the massive amount of data being generated is e...
Maciej Paszkowski-Rogacz, Mikolaj Slabicki, M. Ter...
Background: The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for int...
Heng Li, Liang Guan, Tao Liu, Yiran Guo, Wei-Mou Z...
Background: Expressed sequence tag (EST) analyses provide a rapid and economical means to identify candidate genes that may be involved in a particular biological process. These E...
Mariano Latorre, Herman Silva, Juan Saba, Carito G...
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...