— It is difficult to map many existing learning algorithms onto biological networks because the former require a separate learning network. The computational basis of biological...
Background: Modern developmental biology relies heavily on the analysis of embryonic gene expression patterns. Investigators manually inspect hundreds or thousands of expression p...
Rajalakshmi Gurunathan, Bernard Van Emden, Sethura...
We present a model for predicting HLA class I restricted CTL epitopes. In contrast to almost all other work in this area, we train a single model on epitopes from all HLA alleles a...
David Heckerman, Carl Myers Kadie, Jennifer Listga...
For as long as biologists have been computing alignments of sequences, the question of what values to use for scoring substitutions and gaps has persisted. While some choices for s...
In 2006, a debate has risen on the question of the efficiency of bioinformatics methods to reconstruct mammalian ancestral genomes. Three years later, Gordon et al. (PLoS Genetics,...