Sciweavers

2416 search results - page 394 / 484
» What is a Biological Function
Sort
View
BMCBI
2010
123views more  BMCBI 2010»
15 years 4 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
BMCBI
2010
173views more  BMCBI 2010»
15 years 4 months ago
The Yeast Resource Center Public Image Repository: A large database of fluorescence microscopy images
Background: There is increasing interest in the development of computational methods to analyze fluorescent microscopy images and enable automated large-scale analysis of the subc...
Michael Riffle, Trisha N. Davis
BMCBI
2010
100views more  BMCBI 2010»
15 years 4 months ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...
BMCBI
2010
116views more  BMCBI 2010»
15 years 4 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
BMCBI
2007
181views more  BMCBI 2007»
15 years 4 months ago
ASMPKS: an analysis system for modular polyketide synthases
Background: Polyketides are secondary metabolites of microorganisms with diverse biological activities, including pharmacological functions such as antibiotic, antitumor and agroc...
Hongseok Tae, Eun-Bae Kong, Kiejung Park