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BMCBI
2011
13 years 2 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
JCNS
2011
87views more  JCNS 2011»
13 years 2 months ago
Information-geometric measure of 3-neuron firing patterns characterizes scale-dependence in cortical networks
To understand the functional connectivity of neural networks, it is important to develop simple and incisive descriptors of multineuronal firing patterns. Analysis at the pairwise...
Ifije E. Ohiorhenuan, Jonathan D. Victor
TSE
2011
134views more  TSE 2011»
13 years 2 months ago
Verifying the Evolution of Probability Distributions Governed by a DTMC
— We propose a new probabilistic temporal logic iLTL which captures properties of systems whose state can be represented by probability mass functions (pmf’s). Using iLTL, we c...
YoungMin Kwon, Gul A. Agha
NAR
2010
194views more  NAR 2010»
13 years 2 months ago
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
Alternative splicing is an important mechanism for increasing protein diversity. However, its functional effects are largely unknown. Here, we present our new software workflow co...
Dorothea Emig, Nathan Salomonis, Jan Baumbach, Tho...
BIOINFORMATICS
2011
12 years 11 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...