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BIOINFORMATICS
2006
92views more  BIOINFORMATICS 2006»
13 years 6 months ago
What should be expected from feature selection in small-sample settings
Motivation: High-throughput technologies for rapid measurement of vast numbers of biological variables offer the potential for highly discriminatory diagnosis and prognosis; howev...
Chao Sima, Edward R. Dougherty
BMCBI
2006
111views more  BMCBI 2006»
13 years 6 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
BMCBI
2008
142views more  BMCBI 2008»
13 years 6 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
SDM
2012
SIAM
245views Data Mining» more  SDM 2012»
11 years 9 months ago
Deterministic CUR for Improved Large-Scale Data Analysis: An Empirical Study
Low-rank approximations which are computed from selected rows and columns of a given data matrix have attracted considerable attention lately. They have been proposed as an altern...
Christian Thurau, Kristian Kersting, Christian Bau...
RECOMB
2006
Springer
14 years 7 months ago
RNA Secondary Structure Prediction Via Energy Density Minimization
Abstract. There is a resurgence of interest in RNA secondary structure prediction problem (a.k.a. the RNA folding problem) due to the discovery of many new families of non-coding R...
Can Alkan, Emre Karakoç, Süleyman Cenk...