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TCBB
2011
14 years 11 months ago
Information-Theoretic Model of Evolution over Protein Communication Channel
—In this paper, we propose a communication model of evolution and investigate its information-theoretic bounds. The process of evolution is modeled as the retransmission of infor...
Liuling Gong, Nidhal Bouaynaya, Dan Schonfeld
NIPS
2004
15 years 5 months ago
Probabilistic Inference of Alternative Splicing Events in Microarray Data
Alternative splicing (AS) is an important and frequent step in mammalian gene expression that allows a single gene to specify multiple products, and is crucial for the regulation ...
Ofer Shai, Brendan J. Frey, Quaid Morris, Qun Pan,...
BMCBI
2007
94views more  BMCBI 2007»
15 years 4 months ago
A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays
Background: Affymetrix SNP arrays can interrogate thousands of SNPs at the same time. This allows us to look at the genomic content of cancer cells and to investigate the underlyi...
Philippe Lamy, Claus L. Andersen, Lars Dyrskjot, N...
BMCBI
2004
106views more  BMCBI 2004»
15 years 4 months ago
ESTIMA, a tool for EST management in a multi-project environment
Background: Single-pass, partial sequencing of complementary DNA (cDNA) libraries generates thousands of chromatograms that are processed into high quality expressed sequence tags...
Charu G. Kumar, Richard LeDuc, George Gong, Levan ...
BMCBI
2004
174views more  BMCBI 2004»
15 years 4 months ago
SeeGH - A software tool for visualization of whole genome array comparative genomic hybridization data
Background: Array comparative genomic hybridization (CGH) is a technique which detects copy number differences in DNA segments. Complete sequencing of the human genome and the dev...
Bryan Chi, Ronald J. deLeeuw, Bradley P. Coe, Calu...