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» Yeast Ancestral Genome Reconstructions: The Possibilities of...
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NAR
2011
198views Computer Vision» more  NAR 2011»
12 years 10 months ago
PhylomeDB v3.0: an expanding repository of genome-wide collections of trees, alignments and phylogeny-based orthology and paralo
The growing availability of complete genomic sequences from diverse species has brought about the need to scale up phylogenomic analyses, including the reconstruction of large col...
Jaime Huerta-Cepas, Salvador Capella-Gutiér...
BMCBI
2004
151views more  BMCBI 2004»
13 years 7 months ago
A computational approach for ordering signal transduction pathway components from genomics and proteomics Data
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
Yin Liu, Hongyu Zhao
BIBE
2007
IEEE
127views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
A Heuristic for Phylogenetic Reconstruction Using Transposition
Abstract—Because of the advent of high-throughput sequencing and the consequent reduction in cost of sequencing, many organisms have been completely sequenced and most of their g...
Feng Yue, Meng Zhang, Jijun Tang
BMCBI
2007
182views more  BMCBI 2007»
13 years 7 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2005
94views more  BMCBI 2005»
13 years 7 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya