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BMCBI
2006
13 years 8 months ago
2006
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
BMCBI
2006
13 years 8 months ago
2006
Background: With the advances in DNA sequencer-based technologies, it has become possible to automate several steps of the genotyping process leading to increased throughput. To e...
BMCBI
2006
13 years 8 months ago
2006
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
BMCBI
2006
13 years 8 months ago
2006
Background: Genome annotation can be viewed as an incremental, cooperative, data-driven, knowledge-based process that involves multiple methods to predict gene locations and struc...
BMCBI
2007
13 years 8 months ago
2007
Background: Completion of the human genome sequence along with other species allows for greater understanding of the biochemical mechanisms and processes that govern healthy as we...