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BMCBI
2010
214views more  BMCBI 2010»
13 years 10 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2010
201views more  BMCBI 2010»
13 years 10 months ago
Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...
NAR
2010
173views more  NAR 2010»
13 years 4 months ago
The Protein Naming Utility: a rules database for protein nomenclature
Generation of syntactically correct and unambiguous names for proteins is a challenging, yet vital task for functional annotation processes. Proteins are often named based on homo...
Johannes Goll, Robert Montgomery, Lauren M. Brinka...
BMCBI
2010
120views more  BMCBI 2010»
13 years 10 months ago
Short clones or long clones? A simulation study on the use of paired reads in metagenomics
Background: Metagenomics is the study of environmental samples using sequencing. Rapid advances in sequencing technology are fueling a vast increase in the number and scope of met...
Suparna Mitra, Max Schubach, Daniel H. Huson
BMCBI
2010
108views more  BMCBI 2010»
13 years 7 months ago
Prediction of RNA secondary structure by maximizing pseudo-expected accuracy
Background: Recent studies have revealed the importance of considering the entire distribution of possible secondary structures in RNA secondary structure predictions; therefore, ...
Michiaki Hamada, Kengo Sato, Kiyoshi Asai