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BIOINFORMATICS
2011
13 years 1 months ago
RINQ: Reference-based Indexing for Network Queries
We consider the problem of similarity queries in biological network databases. Given a database of networks, similarity query returns all the database networks whose similarity (i...
Günhan Gülsoy, Tamer Kahveci
BIOINFORMATICS
2011
13 years 4 months ago
Inverse perturbation for optimal intervention in gene regulatory networks
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
Nidhal Bouaynaya, Roman Shterenberg, Dan Schonfeld
BIOINFORMATICS
2011
13 years 4 months ago
All-atom knowledge-based potential for RNA structure prediction and assessment
Motivation: Over the recent years, the vision that RNA simply serves as information transfer molecule has dramatically changed. The study of the sequence/structure/function relati...
Emidio Capriotti, Tomás Norambuena, Marc A....
BIOINFORMATICS
2011
13 years 1 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
DNA
2011
Springer
227views Bioinformatics» more  DNA 2011»
12 years 9 months ago
Cooperative Assembly Systems
Several molecular systems form large-scale objects. One would like to understand their assembly and how this assembly is regulated. As a first step, we investigate the phase trans...
Vincent Danos, Heinz Koeppl, John Wilson-Kanamori