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BIOSYSTEMS
2007
175views more  BIOSYSTEMS 2007»
15 years 4 months ago
Alternative routes and mutational robustness in complex regulatory networks
Alternative pathways through a gene regulation network connect a regulatory molecule to its (indirect) regulatory target via different intermediate regulators. We here show for tw...
Andreas Wagner, Jeremiah Wright
BMCBI
2007
115views more  BMCBI 2007»
15 years 4 months ago
How accurate and statistically robust are catalytic site predictions based on closeness centrality?
Background: We examine the accuracy of enzyme catalytic residue predictions from a network representation of protein structure. In this model, amino acid α-carbons specify vertic...
Eric Chea, Dennis R. Livesay
BMCBI
2007
90views more  BMCBI 2007»
15 years 4 months ago
Gene network interconnectedness and the generalized topological overlap measure
Background: Network methods are increasingly used to represent the interactions of genes and/ or proteins. Genes or proteins that are directly linked may have a similar biological...
Andy M. Yip, Steve Horvath
EJC
2010
15 years 4 months ago
On the distance between the expressions of a permutation
Abstract. We prove that the combinatorial distance between any two reduced expressions of a given permutation of {1, ..., n} in terms of transpositions lies in O(n4), a sharp bound...
Patrick Dehornoy, Marc Autord
ACTA
2006
104views more  ACTA 2006»
15 years 4 months ago
Safe projections of binary data sets
Abstract Selectivity estimation of a boolean query based on frequent itemsets can be solved by describing the problem by a linear program. However, the number of variables in the e...
Nikolaj Tatti