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BMCBI
2006
156views more  BMCBI 2006»
13 years 8 months ago
Bayesian models for pooling microarray studies with multiple sources of replications
Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
Erin M. Conlon, Joon J. Song, Jun S. Liu
BMCBI
2006
102views more  BMCBI 2006»
13 years 8 months ago
UVPAR: fast detection of functional shifts in duplicate genes
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
Vicente Arnau, Miguel Gallach, J. Ignasi Lucas, Ig...
RECOMB
2007
Springer
14 years 8 months ago
GIMscan: A New Statistical Method for Analyzing Whole-Genome Array CGH Data
Genetic instability represents an important type of biological markers for cancer and many other diseases. Array Comparative Genome Hybridization (aCGH) is a high-throughput cytoge...
Yanxin Shi, Fan Guo, Wei Wu, Eric P. Xing
WABI
2007
Springer
139views Bioinformatics» more  WABI 2007»
14 years 2 months ago
Computability of Models for Sequence Assembly
Graph-theoretic models have come to the forefront as some of the most powerful and practical methods for sequence assembly. Simultaneously, the computational hardness of the underl...
Paul Medvedev, Konstantinos Georgiou, Gene Myers, ...
WABI
2007
Springer
110views Bioinformatics» more  WABI 2007»
14 years 2 months ago
Haplotype Inference Via Hierarchical Genotype Parsing
The within-species genetic variation due to recombinations leads to a mosaic-like structure of DNA. This structure can be modeled, e.g. by parsing sample sequences of current DNA w...
Pasi Rastas, Esko Ukkonen